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Location of Port-Wine Stains and the Likelihood of Ophthalmic and/or CNS Complications
Pediatrics 87:323-327, Tallman,B.,et al, 1991
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Article Abstract
Port-wine stains of the eyelids,bilateral distribution of the birthmark, and unilateral port-wine stains involving all three branches of the trigeminal nerve were associated with a significantly higher liklihood of having eye and/or CNS complications.Twenty-four percent of those with bilateral trigeminal nerve port-wine stains had eye and/or CNS involvement compared with 6%of those with unilateral lesions.All those who had eye and/or CNS complications had port-wine stain involvement of the eyelids;in 91%both upper and lower eyelids were involved,whereas in 9%only the lower eyelid was involved.None of those with upper eyelid port-wine stains alone had eye and/or CNS complications.In addition,3(75%)of the 4 subjects with seizures alone had bilateral port-wine stain involvenemt.A third group, those with unilateral V1,V2 and V3 port-wine stains,had eye and/or CNS complications in 3(19%)of 16 subjects.Therefore,persons who have port-wine stains,or bilateral lesions should be screened for glaucoma and have appropriate testing for CNS involvement.
 
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Cobb syndrome
glaucoma
port wine nevus
seizure
skin,lesions in neurologic disorders
Sturge-Weber syndrome

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